Santander UK says it is to cut 111 branches amid a customer drive towards online banking but it expects to retain a “significant” number of the staff affected.
The lender said its decision – aided by COVID-19 disruption – would be implemented by the end of August and leave it with 452 high street sites.
It follows an industry trend over many years that has seen banks move to cut costs and invest in their digital offerings.
The company charted a 33% fall in branch transactions in the two years before the virus crisis.
It reported a further decline of 50% during 2020.
Santander was unable, at this stage, to confirm how many jobs had been placed at risk under the branch shake-up.
Its plans included a major cutback in its office space requirements, which it said was based on staff feedback related to working from home during the pandemic.