Police in the US are searching for a 35-year-old woman accused of killing two of her children before disappearing.

Officers in the state of Colorado have issued an arrest warrant for Kimberlee Singler, who is wanted on suspicion of murder, attempted murder, child abuse and assault.

Police responded to a 911 call about a burglary in 5300 block of Palomino Ranch Point on 19 December.

A nine-year-old girl and a seven-year-old boy were found dead at the scene, according to police.

Singler and her 11-year-old daughter were taken to hospital.

Investigations determined the initial report of a burglary was “unfounded”, police said.

The warrant for Singler’s arrest was obtained on Tuesday but Singler has not been seen since last Saturday.

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The missing mother and her estranged husband have been involved in a years-long divorce case.

In the case, one parent has accused the other of brandishing a knife, and a court has deliberated over polygraph testing and visiting exchanges, according to court records.

Solicitors for both the suspect and her husband could not be reached for comment on Friday.

A spokesperson for the police said the 11-year-old girl is safe and in Colorado Springs but is not with her father.

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The FBI is assisting with the search but police do not believe Singler is in or near Colorado Springs.

“She could be anywhere,” a spokesperson added.

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