A government minister has said he did not approve of moves to break from government guidelines on the rollout of vaccines in areas where the Indian variant has been found – as London’s mayor called for more flexibility.

Asked whether he approved of authorities in Bolton vaccinating “anyone who wants it”, Business Secretary Kwasi Kwarteng told Sky News: “No, I think the government has very clear guidelines in terms of the ordered way in which we roll out the vaccine.”

But it came as Mayor of London Sadiq Khan said he had asked Health Secretary Matt Hancock to give city authorities “the flexibility to give younger people the vaccine, in those parts of London who are concerned about this strain”.

Over the weekend, Bolton distributed more than 6,200 doses of vaccine as it struggled to combat an upsurge in cases, much of which have been blamed on the Indian variant.

While just over 1,300 cases of the variant – also called B.1.617 – have been found in the country so far, Mr Hancock said on Sunday it was “becoming the dominant strain in some parts of the country” such as Bolton and Blackburn.

It prompted authorities in Bolton to encourage all adults to attend vaccination centres to get the jab – despite government guidance recommending everyone over the age of 38 comes forward to get their inoculation, with older and more vulnerable groups having been invited already.

As thousands rushed to take advantage of the offer in Bolton, there were reports that some of those who had the jab were under 18.

Please use Chrome browser for a more accessible video player

Mr Kwarteng said government guidelines had “been working and [it] has been a very effective rollout, and we would suggest that people should do it in the correct order, in the right way.”

Asked whether ministers should pressure local authorities not to break from the guidelines, Mr Kwarteng said: “I don’t know the actual details of what is going on in Bolton but we’ve got very firm guidelines and we want people to follow those.”

Referring to Bolton, he added: “I can see what they are trying to do… but what I’ve said is that there is a really good way that we’ve managed to roll out the vaccine and we would urge people to follow the guidelines that we’ve set out and the method that we’ve used.”

Mr Khan said he disagreed with the government, saying he thought a more “nimble” approach was necessary. London is another area where the Indian variant has been found.

He told Sky News: “In those parts of the country where there are pockets where people have this Indian variant… we should be nimble and we should be giving the vaccine to younger people in those areas. Why? Because the early evidence is if you receive the vaccine, you are less likely to catch this variant, the spread is less serious but also the consequences should you catch it are much less serious as well.

“I’ve asked both Matt Hancock and Nadhim Zahawi, the various ministers, on Friday to give us the flexibility to give younger people the vaccine, in those parts of London that are concerned about this strain.”

Labour shadow foreign secretary Lisa Nandy, who was speaking to Sky News from her constituency in Wigan – less than 10 miles from Bolton – also called on the government to do more listening.

She said: “The biggest thing for us here is that the government starts to listen to us locally.

“When you’ve got local Tory councils saying, ‘look, give us some discretion, give us some leeway to be able to administer the vaccine to as many people as possible as quickly as possible’. I think the government does need to start listening.”

On Sunday, Mr Hancock said in Bolton, where a number of people have ended up in hospitals with the Indian variant, the “vast majority” of those patients had been eligible for a COVID jab but had not yet had one.

He likened the current situation facing the country to “a race between the vaccination programme and the virus”, with the Indian variant having “given the virus some extra legs in that race”.

Mr Hancock told Sky News’ Sophy Ridge On Sunday show he did not rule out different restrictions in parts of the country where infections were not falling as quickly as others.

Dr Helen Wall, who is leading the vaccination effort in Bolton, told BBC Breakfast that, over the weekend, long queues of people were seen waiting for vaccines.

She said before the weekend there were around 10,000 people in the area in the highest priority groups who were yet to be vaccinated.

Please use Chrome browser for a more accessible video player

“We’re seeing people coming forward that clearly had the option to have the jab for some time – older people, disabled people – and they’ve chosen to come forward now,” she said.

“I’m hoping that we’ve made a big dent into that now.”

But it was reported in The Times that teenagers were among those receiving their jabs after local councillors and the local health authorities urged all adults to attend vaccination centres, leading to long queues.

Social media posts over the weekend – from including the chair of Bolton NHS Foundation Trust, Professor Donna Hall – encouraged all adults to get vaccinations.

What I love ❤️ so much about my home town of Bolton is we just crack on. There may be barriers put in our way but we are a strong town with a brilliant partnership & we won’t be broken – Wanderers invite over 16s to get vaccinated at Bolton Stadium 🙌🙌🙌 https://t.co/rijRnKCqCT

One of the members of the Joint Committee on Vaccination and Immunisation (JCVI), Adam Finn, told Sky News there were good reasons why the government’s recommendations were in place.

He said he understood why Mr Khan may want more flexibility to vaccinate younger age groups, but added: “The two issues with that are that, first of all, we’re really not quite sure how well the vaccines will interrupt transmission, particularly for this new variant.

“We do know they protect people against getting sick and that’s something we can hold on to and use as a strategy.

“The other thing is, that after a first dose of these vaccines, it does take two-three weeks at least before that protection begins to emerge, so what you do now is not really going to have much influence over what happens over the next couple of weeks.

“So for those two reasons we do need to think strategically about what we do with the vaccine doses.”

Related posts:

NHS staff were expecting bigger pay rise than government’s offer, MPs told PM rejects claims of ‘moral failure’ by G7 on vaccines – and says Brexit row left no ‘sour taste’ Tory MP told to apologise for acting in ‘threatening and intimidating’ manner towards staff Johnson is desperate not to be Mr Reverse – so for now he is Mr Delay The rules might be gone, but life in England may not be much different after 19 July Labour’s bedrock support from ethnic minorities is eroding, but not enough yet for Tory landslide People guilty of racist abuse of footballers online will be banned from matches, PM says PM had a simple option over stance on taking the knee – but carelessly stumbled into a row Boris Johnson faces more difficulties over Downing Street parties probe as he clings to power Sir Keir Starmer confirms he has received death threats following PM’s Jimmy Savile remarks ‘We’re on the edge of a precipice’: PM warns of ‘very dangerous’ situation in Ukraine amid Russia invasion fears Russia will face ‘protracted crisis’ if it invades Ukraine, Johnson and Biden warn