A man killed in the West Bank on Monday has been identified as a 26-year-old American-Israeli citizen, Elan Ganeles.
He was shot at a road junction near the city of Jericho.
Multiple gunmen reportedly opened fire on the vehicle, according to the Israel Defense Forces (IDF).
Two more vehicles with Israeli number plates were attacked shortly after, but no injuries were reported.
The attackers set fire to their own vehicle and then fled on foot. Road blocks have been set up to try and catch them.
The Israeli military has also confirmed that two manhunts are still under way after three people were shot dead in the West Bank town of Hawara on Sunday.
Two Jewish brothers, Hillel and Yigal Yaniv, were shot at point-blank range in their car by a gunman reportedly wearing a T-shirt bearing the logo of the militant Palestinian group Lions Den.
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It’s not yet known whether this was a targeted attack or a random assault on a car with Israeli number plates passing through a Palestinian town.
A Palestinian man in his mid-30s was later shot and killed during revenge riots in Hawara.
The victim, Sameh Aqtash, had recently returned home from Turkey where he had been working as a volunteer following the deadly earthquakes.
The IDF says it is treating both incidents as terrorism.
Around 400 Israeli settlers are said to have marched on the Palestinian town from nearby settlements.
At least 15 houses were set on fire, as well as 25 cars, while nine Palestinian families had to be rescued from their homes.
Ten Israelis have been arrested in connection with the violence, and investigations are said to be ongoing.
The Jerusalem Post reported that two Israeli journalists were shot at by “a Jewish gunman dressed in black clothes and a military vest and helmet”.
The rioting was condemned by the US and UK governments; the British Ambassador to Israel described the scenes as “terrible” and called on Israel to tackle settler violence.
Speaking to journalists on Monday afternoon, an IDF Spokesman described it as “a horrible night”, adding: “I know it looks very, very bad.”
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The IDF defended its tactics after criticism that it could have done more to prevent the riots, following messages on social media inciting violence.
“It’s too early to say (if operational mistakes were made), but it wasn’t a good day,” admitted the spokesman.
More forces have been deployed to the area to “de-escalate the situation and keep the two sides apart”.
The violence coincided with rare talks between Palestinian and Israeli officials at the Red Sea resort of Aqaba in Jordan.
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The high-ranking security figures, from both sides, met amid escalating violence and agreed to take measures to calm the tensions.
However, shortly after a statement was released, part of which said Israel would halt settlement expansions for six months, Prime Minister Benjamin Netanyahu published a post on Twitter rejecting the statement.